Go to Home - CTRL, ALT, L
Exit the Application - CTRL, Q
Sync - F5
Help - F1
Move focus to next enabled control - Tab
Move the focus to the book above the current selection - Up Arrow
Move the focus of the book to the right of the current selection - Right Arrow
Move the focus of the book to the left of the current selection - Left Arrow
Move the focus of the book below the current selection - Down Arrow
Scroll the list of books up one page (but do not change the current focus) - Page Up
Scroll the list of books down one page (but do not change the current focus) - Page Down
Open selected book to last (go to last page read) - Enter, CTRL O
Sort by Most Recent - CTRL, ALT, R
Sort by Title - CTRL, ALT, T
Sort by Author - CTRL, ALT, U
Next Page - Page Down or Right Arrow
Previous Page - Page Up or Left Arrow
Back - Backspace
Increase Font Size - CTRL, + (doesn't work on comics or content for children)
Decrease Font Size - CTRL, - (doesn't work on comics or content for children)
Bookmark - CTRL, D
Open Notes and Marks (if closed) - CTRL, B
Close Notes and Marks (if opened) - CTRL, B
Go to Location - CTRL, G
Close Book - CTRL, W
Search - CTRL, F
Toggle Full-Screen Mode - F11
Exit Full-Screen Mode - ESC
Single Column - Alt + 1
Two-Column - Alt + 2
Multi-Column - Alt + 3
Open Flashcard Side Panel - Ctrl, Shift, F
Open and close X-Ray for Textbooks - Ctrl, Y (only works on eligible Textbooks)
Flip Flashcards - Ctrl, Space bar (only works when in the Flashcards deck)
Export to Flashcards from Notebook - Ctrl, Shift, N (when using the Notebook)
Export notes from Notebook - Ctrl, Alt, E (when using the Notebook)
To use these shortcuts, you must enable Text-to-Speech first. Press "Ctrl, T" or select the Tools menu and choose Start Text-to-Speech.
Toggle Text-to-Speech - Ctrl, T
Pause or resume reading - Space bar (while in a book)
Read the previous sentence - Ctrl, Shift, Up arrow
Skip forward one sentence - Ctrl, Shift, Down arrow
Increase speech rate - Shift, +
Decrease speech rate - Shift, -
Toggle continuous reading - Ctrl, Shift, C
Note: This feature only works on eligible Kindle content. You can configure the Text-to-Speech language from the System Preferences on your computer.
Go to the next table - T
Go to the previous table - Shift + T
Enter first cell - Shift + ,
Cell to right - Ctrl + Alt + rightArrow
Cell to left - Ctrl + Alt + leftArrow
Cell above - Ctrl + Alt + upArrow
Cell below - Ctrl + Alt + downArrow
Next (Previous) link - K (Shift + K)
Next (Previous) image - G (Shift + G)
Exit table - ,
Reference
https://www.amazon.com/gp/help/customer/display.html?nodeId=GPC7U392HH93VPC8